By James Shepherd, Christopher J. Packard (auth.), Linda L. Gallo (eds.)
The 6th Annual foreign Spring Symposium on overall healthiness Sciences, held in Washington, D. C. , in could 1986, introduced jointly over 650 scientists from 19 international locations to check and replace examine on heart problems. during this quantity, which includes fifty nine chapters, an the world over well-known crew of authors con tribute up to date bills of molecular and mobile procedures happening within the vessel wall in atherogenesis and describe methods to the prevention and remedy of atherosclerosis. the quantity is split into six significant sections. sections take care of present points of lipoprotein metabolism. partly I, we're alerted to the influence on li poprotein metabolism of structural heterogeneity in the 4 huge lipoprotein periods. recognition then turns to the elements that orchestrate lipoprotein metab olism. Apolipoprotein identities, processing, and features are defined, as are the jobs of lipid move proteins in plasma lipoprotein home improvement. Hepatic lipase synthesis and secretion are defined. partly II, Nobel Laureates Michael S. Brown and Joseph L. Goldstein describe mutations within the LDL receptor that show the features of its a variety of domain names and indicate how knowing the LDL receptor has supplied a rational foundation for its rules. A dialogue of the function of receptors in regulating ldl cholesterol uptake through tissues follows, with emphasis on receptor-ligand interactions. extra pathways for ldl cholesterol supply to cells are explored, as are pathways for ldl cholesterol egress.
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Additional info for Cardiovascular Disease: Molecular and Cellular Mechanisms, Prevention, and Treatment
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Cardiovascular Disease: Molecular and Cellular Mechanisms, Prevention, and Treatment by James Shepherd, Christopher J. Packard (auth.), Linda L. Gallo (eds.)