Download e-book for iPad: Allergens and Allergen Immunotherapy by Richard F. Lockey, Dennis K. Ledford

By Richard F. Lockey, Dennis K. Ledford

ISBN-10: 1842145738

ISBN-13: 9781842145739

ISBN-10: 1842145746

ISBN-13: 9781842145746

This 5th version of the bestselling Allergens and Allergen Immunotherapy is now thoroughly up-to-date and revised to incorporate subcutaneous, sublingual, and oral immunomodulator remedies of allergic disease.

The redesigned publication maintains to supply entire insurance of every kind of allergens and allergen vaccines, giving clinicians the basic info they should competently make a prognosis and provide the very best remedies.

The 5th variation comprises many new and revised chapters―particularly within the fields of epidermis testing―and vast updates to the sublingual and oral immunotherapy chapters.

Key positive aspects:

  • Comprehensive – covers an unlimited variety of allergens and allergen immunotherapies, offering all of the invaluable info in a single volume
  • Synoptic – offers the fundamental details utilizing figures and tables for fast entry
  • Up-to-date – contains the very most modern details on subcutaneous, sublingual and oral allergen immunotherapies to provide the very best treatments
  • Reliable – offers uncomplicated details that each one clinicians want to know approximately cross-reactivity between allergens and the way it affects prognosis and remedy, in addition to the major details essential to perform any kind of immunotherapy in a secure and potent demeanour
  • Supplemental varieties – comprises template kinds that may be utilized by the clinician in day-by-day practice

The 5th variation of this vintage textual content remains to be a vital touchstone for any practitioner who conducts epidermis checks and prescribes subcutaneous, sublingual, and oral immunotherapies.

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Extra info for Allergens and Allergen Immunotherapy

Sample text

Early treatment programs were developed by trial and error, and efficacy varied accordingly. In general, skin test reactivity was used for determination of starting doses, their increments, and frequency of administration. Perennial ­rhinitis and asthma mandated uninterrupted treatment schedules, but the superiority of perennial versus preseasonal plans for treatment of hay fever could not be settled by impressions and anecdotal reports. Modifications of schedule were devised for applying the principle of desensitization within compressed time frames.

A large dose of pollen vaccine, calculated as the cumulative total that would be given in the course of a conventional preseason schedule, was emulsified in oil with an emulsion stabilizer, and administered as a single intramuscular injection [118,119]. A number of anecdotal reports by Allergen Immunotherapy in a Historical Perspective Brown spoke of “thousands” of uniformly successful results of treatment with emulsified vaccines of pollen and other airborne allergens [122]. However, adverse reactions consisting of late formation and persistence of nodules, sterile abscesses and granulomata, and a potential for induction of delayed hypersensitivity to injected antigens were found inherent in emulsion therapy.

Strickler’s follow-up report three years later indicated favorable acceptance of intramuscular injection, oral methods, and a combination of both [134]. 14 Although trials during subsequent years supported this early usage [139], there were differing reports varying from only short-term immunizing effects [140] to lack of either clinical benefit [141] or increased tolerance [142]. Despite divergence of opinion, the oral method of preventive therapy remained popular for 50-some years. , the Rhus ivy-oak-sumac group, primula, geranium, tulip, and chrysanthemum).

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Allergens and Allergen Immunotherapy by Richard F. Lockey, Dennis K. Ledford

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